The risk or severity of Tachycardia can be increased when Pseudoephedrine is combined with Aclidinium. The therapeutic efficacy of Acetohexamide can be decreased when used in combination with Pseudoephedrine.Īcetophenazine may decrease the stimulatory activities of Pseudoephedrine. The risk or severity of hypertension can be increased when Pseudoephedrine is combined with Acemetacin.Īcetazolamide may decrease the excretion rate of Pseudoephedrine which could result in a higher serum level. The risk or severity of hypertension can be increased when Pseudoephedrine is combined with Aceclofenac. The therapeutic efficacy of Acebutolol can be decreased when used in combination with Pseudoephedrine. The therapeutic efficacy of Acarbose can be decreased when used in combination with Pseudoephedrine. The risk or severity of adverse effects can be increased when Pseudoephedrine is combined with Abaloparatide. 10 TargetĪ Sodium-dependent noradrenaline transporter 5 Pseudoephedrine also inhibits NF-kappa-B, NFAT, and AP-1. 5 Pseudoephedrine is also a partial agonist of the anococcygeal muscle. The sympathomimetic effects of pseudoephedrine include an increase in mean arterial pressure, heart rate, and chronotropic response of the right atria. 7 Pseudoephedrine is also an inhibitor of norepinephrine, dopamine, and serotonin transporters. 11 This agonism of adrenergic receptors produces vasoconstriction which is used as a decongestant 2, 12, 13, 14, 15, 16, 17, 18 and as a treatment of priapism.
Pseudoephedrine acts mainly as an agonist of alpha adrenergic receptors 6 and less strongly as an agonist of beta adrenergic receptors. 12, 13, 14, 15, 16, 17, 18 Patients should be counselled regarding the risk of central nervous system stimulation. 2, 12, 13, 14, 15, 16, 17, 18 It has a short duration of action unless formulated as an extended release product. Pseudoephedrine causes vasoconstriction which leads to a decongestant effect.
0 kommentar(er)
